Hodgkin's Disease- A cancer of the immune system that is marked by the presence of a type of cell called the Reed Sternberg cell. Symptoms include the painless enlarged lymph nodes, spleen, or other immune tissue. Other symptoms include fever, weight loss, fatigue, or night sweats. Also called Hodgkin's lymphoma.

Adult Hodgkin's lymphoma is a disease in which malignant (cancer) cells form in the lymph system. Because lymph tissue is found throughout the body, Hodgkin's lymphoma can begin in almost any part of the body and spread to almost any tissue or organ in the body.